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H pylori infection

Introduction

Helicobacter pylori (H. pylori) is a type of bacteria that prones to live and attack our stomach. As it adapts to the extreme and acidic environment, gastric acid cannot kill H. pylori thoroughly. With reference to a study carried out by the Faculty of Medicine of the Chinese University of Hong Kong in 2017, about 4.4 billion people worldwide are experienced with H. pylori infection. In Hong Kong, around 50% of the population are infected with it.

There is a higher rate of infection in the age group over 30 than the age group below 30. In a further serious stage, this bacteria could induce chronic gastritis. As a result, gastrointestinal ulcers would also be undergone by 10-15% of patients.
Causes
Causes
  1. H. pylori bacteria is usually transmitted through:
    • Person-to-person (e.g. saliva, vomit or stool)
    • Contaminated food or water
Causes
  1. H. pylori bacteria is usually transmitted through:
    • Person-to-person (e.g. saliva, vomit or stool)
    • Contaminated food or water
Causes
Symptoms
Symptoms
  1. Bloating
  2. Excessive gas
  3. Sudden weight loss
  4. Stomach pain
  5. Loss of appetite

Graph + description of effects + citation, incl. studies for different age groups if applicable

  1. Emara, M. H., Mohamed, S. Y., & Abdel-Aziz, H. R. (2014). Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial. Therapeutic advances in gastroenterology, 7(1), 4-13.
    • Patients supplemented with L. reuteri Gastrus during triple therapy showed significantly less abdominal pain, epigastric pain, bloating and diarrhea compared to the placebo group.
  2. Francavilla, R., Polimeno, L., Demichina, A., Maurogiovanni, G., Principi, B., Scaccianoce, G., … & Versalovic, J. (2014). Lactobacillus reuteri strain combination in Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Journal of clinical gastroenterology, 48(5), 407-413.
    • Patients supplemented with L. reuteri Gastrus during bismuth-containing quadruple therapy for 14 days showed significantly less abdominal pain, abdominal discomfort and bitter taste compared to the placebo group.
  3. Emara, M. H., Mohamed, S. Y., & Abdel-Aziz, H. R. (2014). Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial. Therapeutic advances in gastroenterology, 7(1), 4-13.
    • Patients supplemented with L. reuteri Gastrus during and after triple therapy showed significantly less activity of inflammation compared to the placebo group when followed-up at 8 weeks.
  4. Francavilla, R., Polimeno, L., Demichina, A., Maurogiovanni, G., Principi, B., Scaccianoce, G., … & Versalovic, J. (2014). Lactobacillus reuteri strain combination in Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study. Journal of clinical gastroenterology, 48(5), 407-413.
    • L. reuteri Gastrus has been shown to reduce gastrin-17 levels, an indirect marker of inflammation and progression of the disease.
Alleviation
  1. Take probiotics supplementation with 2 strains L. reuteri ATCC PTA 6475 and L. reuteri DSM 17938 in order to reduce functional abdominal pain and modulate abnormal acid secretion etc
  2. Practice good hygiene routine
    • Wash hands frequently, especially after going to restroom or before eating
    • Drink water which is boiled or from safe sources
    • Food is handled properly and safely cooked
product shot + name  
健胃益生菌

Biogaia Reuteri Gastrus Probiotic Chewable Tablets